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“Purple Drank”, “Sizzurp” or “Lean” typically involves mixing prescription-strength cough syrup containing codeine or hydrocodone with soda and sometimes candy, and it is known for its dangerous and illicit nature.

How does this medication work?

Hydrocodone belongs to the family of medications known as antitussives (cough suppressants). This medication is used to control coughing that is exhausting and nonproductive (nothing is coughed up). It works on the brain to decrease the urge to cough. Hydrocodone is a narcotic medication and therefore can be habit-forming if taken for long periods of time.

How should I use this medication?

Adults:

The recommended dose of hydrocodone for adults is 5 mg (1 teaspoonful [5 mL]) not less than 4 hours apart, after meals and at bedtime with food or a glass of milk. Do not exceed 30 mg (6 doses) in a 24-hour period. The maximum single dose for adults is 15 mg (15 mL).

Recommended dose:

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

Storage:

Store this cough syrup at room temperature, protect it from light and moisture, and keep it out of the reach of children.

What form does this medication come in?

Syrup. Each mL of red-cherry-flavoured syrup contains 1 mg of hydrocodone bitartrate. Nonmedicinal ingredients: artificial cherry flavor, caramel colour, FD&C Red No. 2 Aluminum Lake, hydrochloric acid, methylparaben, propylparaben, purified water, sorbitol, and sucrose.

Who should not take this medication?

Do not take hydrocodone if you:

• are allergic to hydrocodone or any ingredients of the medication
• are allergic to any of the other “opioid”-type medications (e.g., morphine, codeine)
• are experiencing slowed, shallow breathing (respiratory depression)
• are pregnant or breast-feeding
• are taking an MAO inhibitor (e.g., phenelzine, tranylcypromine) or have taken one in the past 2 weeks
• have active alcoholism or are experiencing alcohol withdrawal
• have acute asthma or other obstructive airway diseases (e.g., chronic bronchitis, emphysema), or trouble breathing
• have a blockage of the intestines or a condition that slows down passage of material through the digestive tract
• have a decreased level of consciousness
• have a head injury or increased pressure inside the brain
• have or may have appendicitis or pancreatitis
• Do not give this medication to children less than 18 years of age.

Side effects:

• blurred vision
• constipation (more common with long-term use)
• decreased appetite
• decreased sexual ability or interest in sexual activity
• dizziness
• drowsiness
• dry mouth
• headache
• itching
• lightheadedness, or feeling faint when rising from a sitting or lying position
• nausea
• sweating
• trouble sleeping
• unusual tiredness or weakness
• vomiting
• Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.

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